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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
10.91
Human Site:
S258
Identified Species:
17.14
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S258
K
K
K
Q
R
K
D
S
A
S
E
E
E
A
H
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S258
K
K
Q
Q
H
K
D
S
A
S
E
E
E
A
H
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S258
K
K
K
Q
R
K
D
S
A
G
E
E
E
A
N
Dog
Lupus familis
XP_536242
380
42964
G251
S
K
A
G
E
A
K
G
A
A
D
R
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
G261
E
E
G
A
D
R
N
G
G
P
G
E
D
A
A
Rat
Rattus norvegicus
Q6AYK5
386
43662
A248
E
K
K
R
A
R
D
A
Q
A
S
E
E
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
C255
K
R
K
N
K
T
G
C
T
P
E
L
D
V
N
Chicken
Gallus gallus
XP_420792
364
42082
N230
K
Q
K
E
S
L
E
N
E
F
E
M
N
G
N
Frog
Xenopus laevis
NP_001086609
360
41600
N218
K
K
R
K
I
E
E
N
D
V
H
A
E
T
D
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
N213
Q
N
T
D
G
K
N
N
K
R
Q
K
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
P183
A
E
V
E
E
E
A
P
P
K
K
K
A
K
V
Honey Bee
Apis mellifera
XP_623803
246
28455
N148
K
I
E
T
A
Y
K
N
N
I
Q
D
I
N
S
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
K155
R
K
Q
E
E
T
Q
K
M
E
K
A
Q
K
E
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
S305
N
V
E
S
D
Q
A
S
S
S
K
E
K
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
D55
H
T
S
C
I
S
E
D
E
K
Y
Q
K
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
86.6
86.6
13.3
N.A.
13.3
33.3
N.A.
20
20
20
6.6
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
93.3
93.3
26.6
N.A.
46.6
66.6
N.A.
46.6
53.3
53.3
53.3
N.A.
33.3
33.3
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
14
7
14
7
27
14
0
14
14
34
14
% A
% Cys:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
14
0
27
7
7
0
7
7
14
0
7
% D
% Glu:
14
14
14
20
20
14
20
0
14
7
34
40
34
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
7
7
7
0
7
14
7
7
7
0
0
14
7
% G
% His:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
14
% H
% Ile:
0
7
0
0
14
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
47
47
34
7
7
27
14
7
7
14
20
14
20
14
7
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% M
% Asn:
7
7
0
7
0
0
14
27
7
0
0
0
7
7
20
% N
% Pro:
0
0
0
0
0
0
0
7
7
14
0
0
0
0
0
% P
% Gln:
7
7
14
20
0
7
7
0
7
0
14
7
7
0
0
% Q
% Arg:
7
7
7
7
14
14
0
0
0
7
0
7
0
0
0
% R
% Ser:
7
0
7
7
7
7
0
27
7
20
7
0
0
7
7
% S
% Thr:
0
7
7
7
0
14
0
0
7
0
0
0
0
7
0
% T
% Val:
0
7
7
0
0
0
0
0
0
7
0
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _